Surface Plasmon Resonance: Molecular Interactions and Ligand Binding Analysis

The GMP compliant BiacoreTM T200 system is an established and stateof-the-art instrument for real-time and label-free biomolecular interaction analysis and binding assays. The system is used to deliver high-quality kinetic, binding affinity, concentration, specificity, selectivity, and thermodynamic interaction data, all with high sensitivity. Based on Surface Plasmon Resonance (SPR) technology, the Biacore T200 system significantly enhances performance so that the upper and lower limits of kinetic ranges can be assessed. Moreover, the system enables analysis of interactions between biomolecules ranging from low molecular weight ions to complex viruses. This powerful system has a wide variety of applications from biological research, vaccine development, bio-therapeutics and small molecule drug development, through to immunogenicity studies and quality control8.